SITAYES DM 50 (Sitagliptin + Dapagliflozin + Metformin)

MOA

1. Sitagliptin inhibits DPP-4 enzyme
2. Enhances incretin hormones
3. Increases insulin secretion
4. Dapagliflozin increases glucose excretion
5. Metformin reduces hepatic glucose production
6. Improves insulin sensitivity
7. Provides triple glycemic control

Uses

1. Type 2 diabetes mellitus
2. Poor glycemic control
3. Triple drug therapy
4. Obese diabetics
5. High HbA1c levels
6. Cardiovascular risk reduction
7. Long-term diabetes management

Side Effects

1. GI upset (metformin)
2. Urinary infections
3. Genital infections
4. Hypoglycemia (rare)
5. Dehydration
6. Nausea
7. Dizziness

Precautions

1. Monitor kidney function
2. Maintain hydration
3. Avoid in severe renal disease
4. Watch for infections
5. Take with food
6. Monitor blood sugar
7. Use under doctor supervision

Tags: Sitagliptin 100mg + Dapagliflozin 10mg + Metformin500mg