VALPOSAFE 500CR

COMPOSITION - Sodium Valproate 333 mg + Valproic Acid 145 mg (Controlled Release) Tablets

DESCRIPTION - VALPOSAFE 500 CR is a controlled-release anticonvulsant formulation that enhances gamma-aminobutyric acid (GABA) levels in the brain, increasing inhibitory neurotransmission and stabilizing neuronal firing. This helps suppress abnormal electrical activity responsible for seizures. The controlled-release mechanism ensures sustained drug levels, improving seizure control and reducing dosing frequency.

Uses 

• Epilepsy

• Generalized tonic-clonic seizures

• Partial seizures

• Neurological seizure disorders

• Bipolar disorder (mood stabilization)

Side Effects 

• Nausea or vomiting

• Drowsiness

• Weight gain

• Tremors

• Hair thinning (temporary)

Precautions / Other Important Details

• Use cautiously in patients with liver impairment

• Contraindicated in pregnancy due to teratogenic risk

• Regular monitoring of platelet count may be required