Glimyes-PM2 SR

Glimyes-PM2 SR Tablets

Composition:

• Metformin Hydrochloride (SR)
• Glimepiride
• Pioglitazone Hydrochloride

Description:

Glimyes-PM2 SR Tablets are a combination oral antidiabetic medication used for the management of Type 2 Diabetes Mellitus. This triple-drug combination works synergistically to control blood glucose levels by improving insulin sensitivity, increasing insulin secretion, and reducing hepatic glucose production. The sustained-release (SR) formulation of Metformin ensures prolonged action and better glycemic control.

Mechanism of Action:

• Metformin (SR): Decreases hepatic glucose production and improves insulin sensitivity.
• Glimepiride: Stimulates pancreatic beta cells to release insulin.
• Pioglitazone: Enhances insulin sensitivity in muscle and adipose tissues by acting on PPAR-γ receptors.

Uses:

• Type 2 Diabetes Mellitus
• Poor glycemic control with dual therapy
• Insulin resistance management

Side Effects:

• Hypoglycemia (especially due to Glimepiride)
• Weight gain
• Gastrointestinal disturbances
• Edema (fluid retention)
• Headache

Precautions:

• Monitor blood glucose regularly
• Use cautiously in liver or kidney impairment
• Avoid alcohol consumption
• Not recommended in Type 1 Diabetes
• Monitor for signs of heart failure (Pioglitazone-related)

Tags: Metformin Hydrochloride (SR) Glimepiride Pioglitazone Hydrochloride